A powerful desktop tool for volcano plots, PCA, heatmaps, and statistical testing. Load your data, select your groups, and get publication-ready results — no coding required.
Features
Built by scientists, for scientists. No scripting, no dependencies to install, no cloud uploads.
Interactive volcano plots with adjustable fold-change and p-value thresholds. Click any point to see box plot comparisons.
Principal component analysis with variance explained, sample clustering, and top loading molecules.
Z-score normalized heatmaps of the most significant molecules, with configurable molecule count.
Welch's t-test with automatic group detection. Summary statistics, significance counts, and exportable results.
Automatic blank sample detection with configurable threshold. Values below background noise are filtered out.
Export results to CSV or Excel. Full processing log with every step documented for reproducibility.
Workflow
Load your Skyline CSV or Excel export, and the tool handles charge optimization, duplicate removal, blank filtering, and sample validation automatically.
Download
Download the latest version for your platform. Automatic updates keep you current.
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View all releases on GitHub →